The Hunter lab uses ecological approaches to define the environmental chemistry of the airways, understand how microbes adapt, and how to manipulate this niche to slow disease development. Efforts are focused on three main areas of emphasis:
Lung environmental chemistry
The main research thrust of the lab focuses on host-microbe interactions and probing the effect of in vivo environmental chemistry on the dynamics of polymicrobial infections. For example, the primary sources of energy for bacterial growth in the respiratory tract are poorly characterized. Our lab is defining the microbe-microbe and host-microbe interactions that sustain the bioavailable carbon budget in the infected respiratory tract, and the metabolic strategies cystic fibrosis pathogens use to obtain these resources.